Liquid composition for electronic cigarettes

ABSTRACT

A liquid composition for electronic cigarettes includes a vaporizable base and one or more sympathomimetic stimulants.

BACKGROUND OF THE INVENTION 1. Field of the Invention

The present invention relates a vaporizable liquid composition for usewith smokeless electronic cigarettes (e-cigarettes). More particularly,the invention relates to a vaporizable liquid composition including avaporizable base and a stimulant.

2. The Prior Art

U.S. Patent Application Publication No. US 2015/0150303 to Jensendiscloses an electronic cigarette liquid including a vaporizable base, aflavoring and a non-nicotine stimulant. The non-nicotine stimulantsdisclosed in US 2015/0150303 are caffeine, guarana and kola nut.

Although US 2015/0150303 discloses the incorporation of certainnon-nicotine stimulants in a vaporizable composition for electroniccigarettes, there exists a need for a liquid composition for electroniccigarettes incorporating other types of sympathomimetic stimulants,which have distinctly different chemical structures and effects ascompared to known stimulant compositions. Moreover, there exists a needfor a liquid composition for electronic cigarettes incorporating variousstimulants which may enhance energy, mental focus, alertness, overallcognitive function, and physical performance.

SUMMARY OF THE INVENTION

The invention relates to a vaporizable liquid composition for use withsmokeless electronic cigarettes (e-cigarettes). More particularly, theinvention relates to a vaporizable liquid composition including avaporizable base and a stimulant.

A stimulant incorporated into a liquid composition for electroniccigarettes according to an aspect of the invention may be2-Amino-6-methylheptane.

A stimulant incorporated into a liquid composition for electroniccigarettes according to another aspect of the invention may be2-Amino-5-methylhexane.

A stimulant incorporated into a liquid composition for electroniccigarettes according to another aspect of the invention may be5-Methyl-2-heptanamine.

A stimulant incorporated into a liquid composition for electroniccigarettes according to another aspect of the invention may beHigenamine.

A stimulant incorporated into a liquid composition for electroniccigarettes according to another aspect of the invention may be1,3-Dimethylamylamine.

A stimulant incorporated into a liquid composition for electroniccigarettes according to another aspect of the invention may be1,3-Dimethylbutylamine.

A stimulant incorporated into a liquid composition for electroniccigarettes according to another aspect of the invention may beN,N-Dimethylphenethylamine.

An advantage of a liquid composition for electronic cigarettes accordingto an aspect of the invention is that the liquid composition may includea sympathomimetic stimulant, which may mimic responses due tostimulation of sympathetic nerves and directly or indirectly activateadrenergic receptors by increasing certain naturally occurringcatecholamines such as norepinephrine (noradrenaline), epinephrine(adrenaline) and dopamine levels.

A further advantage of a liquid composition for electronic cigarettesaccording to an aspect of the invention is that the liquid compositionmay incorporate a stimulant having the effects of enhancing energy,mental focus, alertness, overall cognitive function, and physicalperformance.

BRIEF DESCRIPTION OF THE DRAWINGS

Other benefits and features of the present invention will becomeapparent from the following detailed description con-sidered inconnection with the accompanying drawings. It is to be understood,however, that the drawings are designed as an illustration only and notas a definition of the limits of the invention.

In the drawings:

FIG. 1 shows a chemical structure for nicotine;

FIG. 2 shows a chemical structure for caffeine;

FIG. 3 shows a chemical structure for 2-Amino-6-methylheptane;

FIG. 4 shows a chemical structure for 2-Amino-5-methylhexane;

FIG. 5 shows a chemical structure for 5-Methyl-2-heptanamine;

FIG. 6 shows a chemical structure for Higenamine;

FIG. 7 shows a chemical structure for 1,3-Dimethylamylamine;

FIG. 8 shows a chemical structure for 1,3-Dimethylbutylamine; and

FIG. 9 shows a chemical structure for N,N-Dimethylphenethylamine.

DETAILED DESCRIPTION OF THE INVENTION

The invention relates to a vaporizable liquid composition for use withsmokeless electronic cigarettes (e-cigarettes). A vaporizable liquidcomposition according to an aspect of the invention includes avaporizable base. The vaporizable base may include an organic solvent,such as vegetable glycerin, propylene glycol, polyethylene glycol or acombination of two or more of such ingredients.

The vaporizable liquid composition may optionally include a flavoring.The flavoring may be a natural flavoring or an artificial flavoring or acombination of natural and artificial flavorings.

The vaporizable liquid composition may optionally include nicotine.

The vaporizable liquid composition may further includes one or morestimulants. The stimulant or stimulants may serve as a nicotinealternative, enhance a user's energy and/or enhance a user's cognitivefunction.

In one aspect of the invention, the stimulant composition may comprise2-Amino-6-methylheptane. This stimulant composition may also be known byfollowing alternate nomenclatures and/or names: 1,5-Dimethylhexylamine;6-Methyl-2-heptylamine; 6-methylheptan-2-amine; 6-Methyl-2-heptanamine;Octodrine; Vaporpac and/or 2-aminoisoheptane. Accordingly, reference tothe compound 2-Amino-6-methylheptane herein shall be deemed to includeeach of these compounds as well.

In another aspect of the invention, the stimulant composition maycomprise 2-Amino-5-methylhexane. This stimulant composition may also beknown by following alternate nomenclatures and/or names:1,4-Dimethylpentylamine; 1,4-Dimethylamylamine; 5-methyl-2-hexylamine;2-hexanamine, 5-methyl-; 5-methylhexan-2-amine; and/or pentylamine,1,4-dimethyl-. Accordingly, reference to the compound2-Amino-5-methylhexane herein shall be deemed to include each of thesecompounds as well.

In another aspect of the invention, the stimulant composition maycomprise 5-Methyl-2-heptanamine. This stimulant composition may also beknown by following alternate nomenclatures and/or names:5-methylheptan-2-amine; 2-Heptanamine, 5-methyl-; 1,4-Dimethylhexylamineand/or 2-Amino-5-methylheptane. Accordingly, reference to the compound5-Methyl-2-heptanamine herein shall be deemed to include each of thesecompounds as well.

In another aspect of the invention, the stimulant composition maycomprise Higenamine. This stimulant composition may also be known byfollowing alternate nomenclatures and/or names: Norcoclaurine and/orDemethylcoclaurine. Accordingly, reference to the compound Higenamineherein shall be deemed to include each of these compounds as well.

In another aspect of the invention, the stimulant composition maycomprise 1,3-Dimethylamylamine. This stimulant composition may also beknown by following alternate nomenclatures and/or names:1,3-Dimethylpentylamine; 4-methylhexane-2-amine; Methylhexaneamine;2-Amino-4-methylhexane; Methylhexanamine and/or 1,3-DMAA. Accordingly,reference to the compound 1,3-Dimethylamylamine herein shall be deemedto include each of these compounds as well.

In another aspect of the invention, the stimulant composition maycomprise 1,3-Dimethylbutylamine. This stimulant composition may also beknown by following alternate nomenclatures and/or names:4-methylpentan-2-amine; 1,3-Dimethylbutanamine; 2-Amino-4-methylpentane;4-Methyl-2-aminopentane and/or Amp Citrate. Accordingly, reference tothe compound 1,3-Dimethylbutylamine herein shall be deemed to includeeach of these compounds as well.

In another aspect of the invention, the stimulant composition maycomprise N,N-Dimethylphenethylamine. This stimulant composition may alsobe known by following alternate nomenclatures and/or names:Dimethylphenethylamine; N,N-Dimethylphenylethylamine;N,N-Dimethyl-N-phenethylamine; N,N-Dimethyl-2-phenylethylamine;N-Phenethyldimethylamine; Dimethyl-phenethyl-amine;phenethyldimethylamine and/or Eria Jarensis.

The stimulants indicated above may be used alone in a vaporizable liquidcomposition for electronic cigarettes, or various combinations of thestimulants may be used. Additionally, a vaporizable liquid compositionfor electronic cigarettes within the scope of the invention may includenicotine as well as one or more of the stimulants indicated above.

The above-identified stimulants, namely 2-Amino-6-methylheptane,2-Amino-5-methylhexane, 5-Methyl-2-heptanamine, Higenamine,1,3-Dimethylamylamine, 1,3-Dimethylbutylamine andN,N-Dimethylphenethylamine are known as sympathomimetic stimulants. Thisis in contrast to Nicotine, which is a parasympathomimetic stimulant.Moreover, each of these sympathomimetic stimulants have differentiatingchemical structures, and are substantially different in terms ofchemical structure (as can be seen from the drawings figures providedherein) as well in effect when compared to the stimulant caffeine.

In particular, sympathomimetic stimulants, such as2-Amino-6-methylheptane, 2-Amino-5-methylhexane, 5-Methyl-2-heptanamine,Higenamine, 1,3-Dimethylamylamine, 1,3-Dimethylbutylamine andN,N-Dimethylphenethylamine, mimic responses due to stimulation ofsympathetic nerves. These stimulants are able to directly or indirectlyactivate adrenergic receptors by increasing certain naturally occurringcatecholamines, such as norepinephrine (noradrenaline), epinephrine(adrenaline) and dopamine levels.

Dopamine functions as a neurotransmitter in the brain. Increasingdopamine levels may be beneficial as dopamine plays a vital role inbodily motor control, executive functions like mental processes andskills, motivation, mood, arousal and reward. Low dopamine levels canlead to fatigue, addictive behavior, mood swings, memory loss and a lackof motivation.

Epinephrine (adrenaline) is released by the adrenal glands. Its releaseinto the blood stream increases heart rate and blood flow, resulting inmore oxygen and blood flow to muscles, creating an instant source ofenergy and allowing body to react quickly. The natural secretion ofepinephrine is often a result of exercise. Epinephrine has also beenshown to play an important role in long term memory function in humans.

Norepinephrine (noradrenaline), which is also released by the adrenalglands, functions as both a hormone and neurotransmitter in the body.The general function of norepinephrine believed to involve mobilizingthe brain and body for action. In the brain, norepinephrine increasesarousal and alertness, enhances mental cognition and attention, promotesvigilance, and enhances retrieval and formation of memory.

For these reasons, sympathomimetic stimulants, such asAmino-6-methylheptane, 2-Amino-5-methylhexane, 5-Methyl-2-heptanamine,Higenamine, 1,3-Dimethylamylamine, 1,3-Dimethylbutylamine andN,N-Dimethylphenethylamine, when incorporated into a vaporizable liquidcomposition to be used with an electronic cigarette for inhalation andabsorption by a user of the electronic cigarette may enhance a user'senergy, mental focus, alertness, overall cognitive function, andphysical performance.

A liquid composition according to an aspect of the invention may beprovided, for example in a 30 ml, 60 ml or 100 ml bottle. In terms ofdosing, a 30 ml bottle of the vaporizable liquid composition maygenerally contain no less than 0.001 mg and no more than 100 g of thestimulant composition, for example no less than 1 mg and no more than 2g of the stimulant composition.

While a number of embodiments of the present invention have been shownand described, it is obvious that many changes and modifications may bemade thereunto without departing from the spirit and scope of theinvention.

What is claimed is:
 1. A liquid composition for electronic cigarettescomprising: a vaporizable base; and 2-Amino-6-methylheptane.
 2. A liquidcomposition for electronic cigarettes comprising: a vaporizable base;and 2-Amino-5-methylhexane.
 3. A liquid composition for electroniccigarettes comprising: a vaporizable base; and 5-Methyl-2-heptanamine.4. A liquid composition for electronic cigarettes comprising: avaporizable base; and Higenamine.
 5. A liquid composition for electroniccigarettes comprising: a vaporizable base; and 1,3-Dimethylamylamine. 6.A liquid composition for electronic cigarettes comprising: a vaporizablebase; and 1,3-Dimethylbutylamine.
 7. A liquid composition for electroniccigarettes comprising: a vaporizable base; andN,N-Dimethylphenethylamine.